Phân tích đặc điểm sử dụng enoxaparin trên người bệnh điều trị nội trú tại Viện Tim mạch - Bệnh viện Trung ương Quân đội 108

Abstract

Objective: To evaluate some characteristics in the use of enoxaparin, contributing to improving the quality of treatment. Subject and method: A retrospective study was performed on 111 patients prescribed enoxaparin from September 01 to October 30, 2020. Result: 67.6% of them were male, and mean age was 63.5 ± 16.1 years, the rate of subjects with more than one disease 66.7%. The proportion of inappropriate was high, 30.6% in the prophylaxis group and 32.9% in the treatment group. 60.4% was indicated enoxaparin concomitantly with drugs with a serious interaction, which increased the risk of bleeding but only one case had a bleeding event (0.9%). Conclusion: The administration of enoxaparin in most cases is consistent with the product instructions and treatment guidelines. However, the proportion of inappropriate enoxaparin was still relatively high, 30.6% in the prophylaxis group and 32.9% in the treatment group. 60.4% was indicated enoxaparin concomitantly with drugs with a serious interaction, which increased the risk of bleeding but only one case had a bleeding event (0.9%). So clinical pharmacological interventions are necessary to contribute to ensuring safety and improving the quality of treatment.