Pemphigus vulgaris với tổn thương chỉ ở niêm mạc miệng

Abstract

Pemphigus vulgaris is an autoimmune blistering disease affecting the skin and mucous membranes. The disease accounts for about 60 - 70% of all forms of pemphigus. The disease is common in people 40 - 50 years old. In 50 - 70% of cases, the initial manifestations of pemphigus vulgaris are lesions in the oral cavity often precede those on the skin by many months or may remain as the only symptoms of the disease [1]. But it is unusual for the disease to present with initial and solitairy persistent lip lesions [2] or mucosa in the cheeks and frogs without progression to any other location. We report a 46-year-old woman with multiple lesions only in the cheek mucosa, palate, gums and no skin lesions. Clinically similar to oral aphthose disease and water-borne lichen disease, but histopathological evaluation showed the unexpected results of suprabas alacantholysis and cleft compatible with pemphigus vulgaris. Conclusion: Mouth mucosal ulcer may be the initial and sole manifestation of pemphigus vulgaris.