ISSN: 1859 - 2872
Comparison of itraconazole and griseofulvin for treatment of tinea corporis in Bac Ninh Dermatology Hospital
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Objective: To compare the efficacy of oral itraconazole with griseofulvin for tinea corporis treatment at Bac Ninh Dermatologic Hospital. Subject and method: A randomized, comparative and prospective study was conducted to compare 66 patients with tinea corporis at Bac Ninh Dermatologic Hospital. These patients were divided into 2 groups: Group 1: Consisted of 31 patients treated with oral Itraconazole (Kbat), and Group 2: Had 35 patients treated with oral Griseofulvin. Result: The result of tinea corporis treatment both clinically and microscopically was the same in two groups. The adverse effects were most seen in the group treated with oral Itraconazole, and the cost for treatment in the Itraconazole group was 7 times higher than in the Griseofulvin group. Conclusion: Oral griseofulvin for tinea corporis was effective and not too pricey.
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2. Lachapelle JM, De Doncker P, Tennstedt D, Cauwenbergh G, Janssen PA (1992) Itraconazolee compared with griseofulvin in the treatment of tinea corporis/cruris and tinea pedis/manus: An interpretation of the clinical results of all completed double-blind studies with respect to the pharmacokinetic profile. Dermatology 184(1): 45-50.
3. Panagiotidou D, Kousidou T, Chaidemenos G, Karakatsanis G, Kalogeropoulou A, Teknetzis A, Chatzopoulou E, Michailidis D (1992) A comparison of itraconazolee and griseofulvin in the treatment of tinea corporis and tinea cruris: a double-blind study. J Int Med Res 20(5): 392-400.
4. Bui Van Duc, Nguyen Tat Thang et al (2007) Compare the efficacy of single dose itraconazole and fluconazole in drug addicts with pityriasis versicolor. Journal of Medicine in Ho Chi Minh City 11: 264-271.
5. Sharma P, Bhalla M, Thami GP, Chander J (2019) Evaluation of efficacy and safety of oral terbinafine and itraconazolee combination therapy in the management of dermatophytosis. J Dermatolog Treat: 1-5.
6. Goh CL, Tay YK, Ali KB, Koh MT, Seow CS (1994) In vitro evaluation of griseofulvin, ketoconazole, and itraconazolee against various dermatophytes in Singapore. Int J Dermatol 33(10): 733-777.
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