ISSN: 1859 - 2872
Case report: Successful treatment of Candidal granuloma caused by Candida parapsilosis with oral fluconazole and terbinafine
Main Article Content
Keywords
Candida parapsilosis, Candidal granuloma, fluconazole, terbinafine
Tóm tắt
Candidal granuloma is a rare disease and treatment is still difficult in clinical practice. This disease is common in immunocompromised patients. Herein, we report a case of a 63-year-old man who presented with Candidal granuloma caused by Candida parapsilosis. The diagnosis was confirmed according to fungal culture. The patient was successfully treated with oral fluconazole and terbinafine. After 2 months, the skin lesions were fully resolved and after 6 months of follow-up, there was no recurrence.
Article Details
Các tài liệu tham khảo
1. Asogan M, Kim HY, Kidd S, Alastruey-Izquierdo A, Govender NP, Dao A, Shin JH, Heim J, Ford NP, Gigante V, Sati H, Morrissey CO, Alffenaar JW, Beardsley J (2024) Candida parapsilosis: A systematic review to inform the World Health Organization fungal priority pathogens list. Med Mycol 62(6):myad131.
2. Díaz-García J, Machado M, Alcalá L, Reigadas E,Pérez-Ayala A, Gómez-García de la Pedrosa E, Gónzalez-Romo F, Cuétara MS, García-Esteban C,Quiles-Melero I, Zurita ND, Muñoz-Algarra M, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J (2023) Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022. Antimicrob Agents Chemother 67(11):e0098623. doi: 10.1128/aac.00986-23.
3. Ge G, Li DM, Mei H, Lu GX, Zheng HL, Liu WD, Shi DM (2019) Different toenail onychomycosis due to Rhodotorula mucilaginosa and Candida parapsilosis in an immu-nocopetent young adult. Med Mycol Case Rep 28(24): 69-71.
4. Ge G, Yang ZY, Li DM, Hoog GS, Shi DM (2019) Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis. Medical Mycol Case Rep 16(24): 48-50.
5. Hauser FV, Rothman S (1950) Monilial granuloma; report of a case and review of the literature. Arch Dermatol Syphilol 61(2): 297-310.
6. Honda Y, Hattori Y, Treashima T, Manabe T, Tanabe H, Miyachi Y (2017) Plantar wart-like Candida granuloma in a patient with myelodysplastic syndrome. J Dermatol 44(11): 298-912.
7. Kang S, Amagai M, Bruckner AL, Enk AH, Margolis DJ, McMichael AJ, Orringer JS. eds (2019) Fitzpatrick's Dermatology, 9e. McGraw-Hill Education: 2952.
8. Koklu E, Gunes T, Kurtoglu S, Gokoglu S, Koklu S (2007) Onychomycosis in a premature infant caused by Candida parapsilosis. Pediatr Dermatol 24(2): 155-156.
9. Mesini A, Mikulska M, Giacobbe DR, Del Puente F, Gandolfo N, Codda G, Orsi A, Tassinari F, Beltramini S, Marchese A, Icardi G, Del Bono V, Viscoli C (2020) Changing epidemiology of candidaemia: Increase in fluconazole-resistant Candida parapsilosis. Mycoses 63(4): 361-368.
10. Noguchi H, Matsumoto T, Kimura U, Hiruma M, Kano R, Yaguchi T, Fukushima S, IHN H (2019) Fungal melanonychia caused by Candida parapsilosis successfully treated with oral fosravucanazole. J Dermatol 1(3): 1-3.
11. Qin J, Yang H, Shan Z, Jiang L, Zhang Q (2021) Clinical efficacy and safety of antifungal drugs for the treatment of Candida parapsilosis infections: A systematic review and network meta-analysis. J Med Microbiol 70(10): 001434.
12. Quindós G (2014) Epidemiology of candidaemia and invasive candidiasis. A changing face. Rev Iberoam Micol 31(1):42-8. doi: 10.1016/j.riam.2013.10.001.
13. Sayed MA, Abdel-Rahman TMA, Hassaneen HM, El Kholy AA and Naguib RM (2014) Effect of Fluconazole and Terbinafine on the Activities of Lanosterol 14 α-Demethylase and Squalene Epoxidase in Ergosterol Biosynthetic Pathway. Egypt. J. Bot 54(2): 247-262.
14. Subramanya SH, Hamal DP, Nayak NR, Gokhale SS (2016) Onychomycosis due to Candida parapsilosis in a child with ventricular septal defect: An unusual predisposition. Case Rep Pediatr. 2016:7026068. doi: 10.1155/2016/7026068.
15. Subramanya SH, Subedi SJ, Metok Y, Kumar A, Prakash PY, Nayak NR (2019) Distal and lateral subungual onychomycosis of the finger nail in a neonate: a rare case. BMC Pediatr 19(1):168.
16. Trofa D, Gácser A, Nosanchuk JD (2008) Candida parapsilosis, an emerging fungal pathogen. Clin Microbiol Rev 21(4): 606-625.
17. Weems JJ Jr (1992) Candida parapsilosis: epidemiology, pathogenicity, clinical manifestations, and antimicrobial susceptibility. Clin. Infect. Dis. 14:756–766.
18. Wu J, Tan J, Yang H, Gao Z, Yang L (2021) Two cases of primary cutaneous candidiasis caused by Candida parapsilosis: A report and literature review. J Mycol Med 31(3): 101158.
19. Xi LY, Li XQ, Zhang JM, Lu CM, Xie T, Yin RF (2007) Good response in a patient with deep-seated subcutaneous ulcer due to Candida species. Mycopathologia 164(2): 77-80.
2. Díaz-García J, Machado M, Alcalá L, Reigadas E,Pérez-Ayala A, Gómez-García de la Pedrosa E, Gónzalez-Romo F, Cuétara MS, García-Esteban C,Quiles-Melero I, Zurita ND, Muñoz-Algarra M, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J (2023) Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022. Antimicrob Agents Chemother 67(11):e0098623. doi: 10.1128/aac.00986-23.
3. Ge G, Li DM, Mei H, Lu GX, Zheng HL, Liu WD, Shi DM (2019) Different toenail onychomycosis due to Rhodotorula mucilaginosa and Candida parapsilosis in an immu-nocopetent young adult. Med Mycol Case Rep 28(24): 69-71.
4. Ge G, Yang ZY, Li DM, Hoog GS, Shi DM (2019) Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis. Medical Mycol Case Rep 16(24): 48-50.
5. Hauser FV, Rothman S (1950) Monilial granuloma; report of a case and review of the literature. Arch Dermatol Syphilol 61(2): 297-310.
6. Honda Y, Hattori Y, Treashima T, Manabe T, Tanabe H, Miyachi Y (2017) Plantar wart-like Candida granuloma in a patient with myelodysplastic syndrome. J Dermatol 44(11): 298-912.
7. Kang S, Amagai M, Bruckner AL, Enk AH, Margolis DJ, McMichael AJ, Orringer JS. eds (2019) Fitzpatrick's Dermatology, 9e. McGraw-Hill Education: 2952.
8. Koklu E, Gunes T, Kurtoglu S, Gokoglu S, Koklu S (2007) Onychomycosis in a premature infant caused by Candida parapsilosis. Pediatr Dermatol 24(2): 155-156.
9. Mesini A, Mikulska M, Giacobbe DR, Del Puente F, Gandolfo N, Codda G, Orsi A, Tassinari F, Beltramini S, Marchese A, Icardi G, Del Bono V, Viscoli C (2020) Changing epidemiology of candidaemia: Increase in fluconazole-resistant Candida parapsilosis. Mycoses 63(4): 361-368.
10. Noguchi H, Matsumoto T, Kimura U, Hiruma M, Kano R, Yaguchi T, Fukushima S, IHN H (2019) Fungal melanonychia caused by Candida parapsilosis successfully treated with oral fosravucanazole. J Dermatol 1(3): 1-3.
11. Qin J, Yang H, Shan Z, Jiang L, Zhang Q (2021) Clinical efficacy and safety of antifungal drugs for the treatment of Candida parapsilosis infections: A systematic review and network meta-analysis. J Med Microbiol 70(10): 001434.
12. Quindós G (2014) Epidemiology of candidaemia and invasive candidiasis. A changing face. Rev Iberoam Micol 31(1):42-8. doi: 10.1016/j.riam.2013.10.001.
13. Sayed MA, Abdel-Rahman TMA, Hassaneen HM, El Kholy AA and Naguib RM (2014) Effect of Fluconazole and Terbinafine on the Activities of Lanosterol 14 α-Demethylase and Squalene Epoxidase in Ergosterol Biosynthetic Pathway. Egypt. J. Bot 54(2): 247-262.
14. Subramanya SH, Hamal DP, Nayak NR, Gokhale SS (2016) Onychomycosis due to Candida parapsilosis in a child with ventricular septal defect: An unusual predisposition. Case Rep Pediatr. 2016:7026068. doi: 10.1155/2016/7026068.
15. Subramanya SH, Subedi SJ, Metok Y, Kumar A, Prakash PY, Nayak NR (2019) Distal and lateral subungual onychomycosis of the finger nail in a neonate: a rare case. BMC Pediatr 19(1):168.
16. Trofa D, Gácser A, Nosanchuk JD (2008) Candida parapsilosis, an emerging fungal pathogen. Clin Microbiol Rev 21(4): 606-625.
17. Weems JJ Jr (1992) Candida parapsilosis: epidemiology, pathogenicity, clinical manifestations, and antimicrobial susceptibility. Clin. Infect. Dis. 14:756–766.
18. Wu J, Tan J, Yang H, Gao Z, Yang L (2021) Two cases of primary cutaneous candidiasis caused by Candida parapsilosis: A report and literature review. J Mycol Med 31(3): 101158.
19. Xi LY, Li XQ, Zhang JM, Lu CM, Xie T, Yin RF (2007) Good response in a patient with deep-seated subcutaneous ulcer due to Candida species. Mycopathologia 164(2): 77-80.