Evaluating several clinical and subclinical characteristics of patients pre- and post-kidney transplant at 103 Military Hospital

Tóm tắt

Objective: To describe several clinical and subclinical characteristics of patients before and after 6 months of kidney transplant at 103 Military Hospital. Subject and method: From March 2018 to April 2020, a prospective, descriptive study enrolled 75 recipients with 6 months after renal transplant at 103 Military Hospital. Result: Prior to transplantation, 80.3% of patients received dialysis with an artificial kidney, while 9.8% received medical treatment; more than 90% of patients had hypertension, anemia, and dyslipidemia, with 43.8% having residual urine loss. The prevalence of HBV and HCV infection were 24.1%, and 95.5% of patients having HLA compatibility from 1-6/6 AG. There was a significant difference in urea, creatinine, uric acid, cholesterol, triglycerides, LDL-C, HDL-C, and hemoglobin before and after transplantation. However, after transplantation, 17.3% and 41.3% of patients had increased urea and creatinine, respectively. There were a 9.3% decrease in glomerular filtration rate and a 5.3% increase in proteinuria. After 6 months of kidney transplantation, indicators such as hypertension, increased CRP, anemia, and left ventricular hypertrophy significantly improved. Conclusion: Six months after transplantation, patients with end-stage renal disease improved in several clinical and subclinical indicators. Patients may still experience several metabolic disorders after transplantation, such as diabetes, decreased glomerular filtration rate, and increased proteinuria.