SARS-CoV-2 variants circulating in Vietnam, April 2020–October 2021

  • Nghiem Xuan Hoan 108 Military Central Hospital, Vietnamese-German Center for Medical Research
  • Phan Quoc Hoan 108 Military Central Hospital, Vietnamese-German Center for Medical Research
  • Nguyen Dang Manh 108 Military Central Hospital, Vietnamese-German Center for Medical Research
  • Le Huu Song 108 Military Central Hospital, Vietnamese-German Center for Medical Research

Main Article Content

Keywords

SARS-CoV-2, covid-19, mutation, deletion, variants, Vietnam

Tóm tắt

Objective: Several distinct severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have emerged in different regions worldwide, including Vietnam. This study was conducted is to understand the molecularly genetic epidemiology of SARS-CoV-2 which has not yet been systematically investigated in Vietnamese clinical setting. Subject and method: We analyzed 671 Vietnamese full-length SARS-CoV-2 sequences available on the Global Initiative on Sharing All Influenza Data (GISAID) with data available by 19 October 2021. Sequence variation was done using CoVsurver mutations App (https://www.gisaid.org/epiflu-applications/covsurver-mutations-app/). Phylogenetic tree was built using nextclade algorithms. Result: Our report highlighted that there has been a substantial change in the molecular epidemiology of SARS-CoV-2 circulating through last three waves and ongoing wave of COVID-19. Currently, the Delta variant was dominant with widespread national level. The Alpha variant was almost disappeared and other VOCs, including Beta, Gamma were speculated to be not circulating yet in Vietnam. Conclusion: Surveillance of the emergent variants of SARS-CoV-2 requires an expanded research program to improve our understanding of emerging SARS-CoV-2 mutations profile and their impact on the protective immunity against variants with these mutations. In addition, our surveillance for molecular epidemiology of SARS-CoV-2 in Vietnam will contribute to the efforts at the global levels to fight the pandemic.

Article Details

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Dec 13, 2021
DOI: https://doi.org/10.52389/ydls.v16iTA.1112
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Tập 16 - Số tiếng Anh 12/2021
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Trích dẫn bài viết này
HoanN. X., HoanP. Q., ManhN. D., & SongL. H. (2021). SARS-CoV-2 variants circulating in Vietnam, April 2020–October 2021. Journal of 108 - Clinical Medicine and Phamarcy, 16(TA). https://doi.org/10.52389/ydls.v16iTA.1112